NLRP3 inflammasome: a promising target in ischemic stroke-Reference-Cited by-同舟云学术

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NLRP3 inflammasome: a promising target in ischemic stroke

Published:2016-08-30 Issue:1 Volume:66 Page:17-24
ISSN:1023-3830
Container-title:Inflammation Research
language:en
Short-container-title:Inflamm. Res.

Author:

Gao Li,Dong Qing,Song Zhenghong,Shen Fei,Shi Jianquan,Li Yansheng

Funder

Research Seed Training Program of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University

Clinical Research Cultivation and Innovation Fund of Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,Immunology

Link

http://link.springer.com/content/pdf/10.1007/s00011-016-0981-7.pdf

Reference59 articles.

1. Lambertsen KL, Biber K, Finsen B. Inflammatory cytokines in experimental and human stroke. J Cereb Blood Flow Metab. 2012;32:1677–98.

2. Fu Y, Liu Q, Anrather J, Shi FD. Immune interventions in stroke. Nat Rev Neurol. 2015;11:524–35.

3. de Abulafia DP. Rivero Vaccari JP, Lozano JD, Lotocki G, Keane RW, Dietrich WD. Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. J Cereb Blood Flow Metab. 2009;29:534–44.

4. Savage CD, Lopez-Castejon G, Denes A, Brough D. NLRP3-inflammasome activating DAMPs stimulate an inflammatory response in glia in the absence of priming which contributes to brain inflammation after injury. Front Immunol. 2012;3:288.

5. Gustin A, Kirchmeyer M, Koncina E, Felten P, Losciuto S, Heurtaux T, Tardivel A, Heuschling P, Dostert C. NLRP3 inflammasome is expressed and functional in mouse brain microglia but not in astrocytes. PLoS One. 2015;10:e0130624.

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