PKA regulates HMGB1 through activation of IGFBP-3 and SIRT1 in human retinal endothelial cells cultured in high glucose
Author:
Funder
National Eye Institute
Research to Prevent Blindness
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,Immunology
Link
http://link.springer.com/article/10.1007/s00011-018-1196-x/fulltext.html
Reference30 articles.
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2. Tang J, Kern TS. Inflammation in diabetic retinopathy. Progress Retinal Eye Res 2011;30:343–58.
3. Abcouwer SF, Lin CM, Shanmugam S, et al. Minocycline prevents retinal inflammation and vascular permeability following ischemia-reperfusion injury. J Neuroinflamm. 2013;10:149.
4. Zhang Q, Steinle JJ. IGFBP-3 inhibits TNF-alpha production and TNFR-2 signaling to protect against Retinal Endothelial Cell Apoptosis. Microvasc Res. 2014;95:76–81.
5. Zhang Q, Guy K, Pagadala J, et al. Compound 49b prevents diabetes-induced apoptosis through increased IGFBP-3 Levels. Investig Ophthalmol Vis Sci. 2012; 53 3004–13.
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