Nafamostat mesilate prevented caerulein-induced pancreatic injury by targeting HDAC6-mediated NLRP3 inflammasome activation
Author:
Funder
National Natural Science Foundation of China
Natural Science Foundation of Sichuan Province
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,Immunology
Link
https://link.springer.com/content/pdf/10.1007/s00011-023-01794-0.pdf
Reference38 articles.
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2. Liu R, Qi H, Wang J, Wang Y, Cui L, Wen Y, et al. Ulinastatin activates the renin-angiotensin system to ameliorate the pathophysiology of severe acute pancreatitis. J Gastroenterol Hepatol. 2014;29:1328–37.
3. Ruud TE, Aasen AO, Stadaas JO, Aune S. Effects on peritoneal proteolysis and hemodynamics of prophylactic and therapeutic infusions of high doses of aprotinin in experimental acute pancreatitis. Scand J Gastroenterol. 1986;21:1011–7.
4. Wisner JR Jr, Ozawa S, Renner IG. The effects of nafamostat mesilate (FUT-175) on caerulein-induced acute pancreatitis in the rat. Int J Pancreatol. 1989;4:383–90.
5. Wisner JR Jr, Renner IG, Grendell JH, Niederau C, Ferrell LD. Gabexate mesilate (FOY) protects against ceruletide-induced acute pancreatitis in the rat. Pancreas. 1987;2:181–6.
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