Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54-Reference-Cited by-同舟云学术

Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54

Published:2011-07-22 Issue:11 Volume:89 Page:1149-1161
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Rowe Steven M.,Sloane Peter,Tang Li Ping,Backer Kyle,Mazur Marina,Buckley-Lanier Jessica,Nudelman Igor,Belakhov Valery,Bebok Zsuzsa,Schwiebert Erik,Baasov Timor,Bedwell David M.

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00109-011-0787-6.pdf

Reference45 articles.

1. Rowe SM, Miller S, Sorscher EJ (2005) Cystic fibrosis. N Engl J Med 352:1992–2001

2. Anonymous (1993) Correlation between genotype and phenotype in patients with cystic fibrosis. The Cystic Fibrosis Genotype-Phenotype Consortium. N Engl J Med 329:1308–1313

3. Shoshani T, Kerem E, Szeinberg A, Augarten A, Yahav Y, Cohen D, Rivlin J, Tal A, Kerem B (1994) Similar levels of mRNA from the W1282X and the delta F508 cystic fibrosis alleles, in nasal epithelial cells. J Clin Invest 93:1502–1507

4. Kerem E (2004) Pharmacologic therapy for stop mutations: how much CFTR activity is enough? Curr Opin Pulm Med 10:547–552

5. Keeling KM, Brooks DA, Hopwood JJ, Li P, Thompson JN, Bedwell DM (2001) Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of alpha-l-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation. Hum Mol Genet 10:291–299

Cited by 66 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations;Frontiers in Pharmacology;2024-04-25

2. Small molecule modulators of cystic fibrosis transmembrane conductance regulator (CFTR): Structure, classification, and mechanisms;European Journal of Medicinal Chemistry;2024-02

3. Aminoglycoside Induced Nephrotoxicity: Pharmacokinetics, Epidemiology, Risk Factors, Pathogenesis, and Prevention;Reference Module in Biomedical Sciences;2024

4. Pharmaceuticals Promoting Premature Termination Codon Readthrough: Progress in Development;Biomolecules;2023-06-14

5. Functional Restoration of BRCA1 Nonsense Mutations by Aminoglycoside-Induced Readthrough;Frontiers in Pharmacology;2022-06-28