Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer-Reference-Cited by-同舟云学术

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Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer

Published:2010-05-28 Issue:9 Volume:88 Page:941-952
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Chen Guang,Yang Na,Wang Xiang,Zheng Si-Yuan,Chen Yi,Tong Lin-Jiang,Li Yi-Xue,Meng Ling-Hua,Ding Jian

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00109-010-0635-0.pdf

Reference35 articles.

1. Ma XM, Blenis J (2009) Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 10:307–318. doi: 10.1038/nrm2672

2. Guertin DA, Sabatini DM (2007) Defining the role of mTOR in cancer. Cancer Cell 12:9–22. doi: 10.1016/j.ccr.2007.05.008

3. Hudes G, Carducci M, Tomczak P, Dutcher J, Figlin R, Kapoor A, Staroslawska E, Sosman J, McDermott D, Bodrogi I, Kovacevic Z, Lesovoy V, Schmidt-Wolf IG, Barbarash O, Gokmen E, O’Toole T, Lustgarten S, Moore L, Motzer RJ (2007) Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 356:2271–2281. doi: 10.1056/NEJMoa066838

4. Motzer RJ, Escudier B, Oudard S, Hutson TE, Porta C, Bracarda S, Grunwald V, Thompson JA, Figlin RA, Hollaender N, Urbanowitz G, Berg WJ, Kay A, Lebwohl D, Ravaud A (2008) Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 372:449–456. doi: 10.1016/S0140-6736(08)61039-9

5. Neshat MS, Mellinghoff IK, Tran C, Stiles B, Thomas G, Petersen R, Frost P, Gibbons JJ, Wu H, Sawyers CL (2001) Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. Proc Natl Acad Sci USA 98:10314–10319. doi: 10.1073/pnas.171076798

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2. p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth;Nature Cell Biology;2020-08-17

3. p27 regulates the autophagy-lysosomal pathway via the control of Ragulator and mTOR activity in amino acid deprived cells;2020-01-07

4. Influence of the HDAC Inhibitor Valproic Acid on the Growth and Proliferation of Temsirolimus-Resistant Prostate Cancer Cells In Vitro;Cancers;2019-04-19

5. Sulforaphane as an adjunctive to everolimus counteracts everolimus resistance in renal cancer cell lines;Phytomedicine;2017-04

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