The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich’s ataxia-Reference-Cited by-同舟云学术

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The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich’s ataxia

Published:2009-12-09 Issue:4 Volume:88 Page:323-329
ISSN:0946-2716
Container-title:Journal of Molecular Medicine
language:en
Short-container-title:J Mol Med

Author:

Richardson Des R.,Huang Michael L-H.,Whitnall Megan,Becker Erika M.,Ponka Prem,Suryo Rahmanto Yohan

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Drug Discovery,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00109-009-0565-x.pdf

Reference50 articles.

1. Becker E, Richardson DR (2001) Frataxin: its role in iron metabolism and the pathogenesis of Friedreich’s ataxia. Int J Biochem Cell Biol 33:1–10

2. Pandolfo M (2003) Friedreich ataxia. Semin Pediatr Neurol 10:163–172

3. Puccio H, Simon D, Cossee M, Criqui-Filipe P, Tiziano F, Melki J, Hindelang C, Matyas R, Rustin P, Koenig M (2001) Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat Genet 27:181–186

4. Richardson DR, Mouralian C, Ponka P, Becker E (2001) Development of potential iron chelators for the treatment of Friedreich’s ataxia: ligands that mobilize mitochondrial iron. Biochim Biophys Acta 1536:133–140

5. Boddaert N, Le Quan Sang KH, Rotig A, Leroy-Willig A, Gallet S, Brunelle F, Sidi D, Thalabard JC, Munnich A, Cabantchik ZI (2007) Selective iron chelation in Friedreich ataxia: biologic and clinical implications. Blood 110:401–408

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