Klotho recovery by genistein via promoter histone acetylation and DNA demethylation mitigates renal fibrosis in mice
Author:
Funder
Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Drug Discovery,Molecular Medicine
Link
http://link.springer.com/article/10.1007/s00109-019-01759-z/fulltext.html
Reference51 articles.
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3. Wing MR, Ramezani A, Gill HS, Devaney JM, Raj DS (2013) Epigenetics of progression of chronic kidney disease: fact or fantasy? Semin Nephrol 33:363–374
4. Ko Y-A, Mohtat D, Suzuki M, Park ASD, Izquierdo MC, Han SY, Kang HM, Si H, Hostetter T, Pullman JM, Fazzari M, Verma A, Zheng D, Greally JM, Susztak K (2013) Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development. Genome Biol 14:R108
5. Smyth LJ, McKay GJ, Maxwell AP, McKnight AJ (2014) DNA hypermethylation and DNA hypomethylation is present at different loci in chronic kidney disease. Epigenetics 9:366–376
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