Targeting erythrocyte-mediated hypoxia to alleviate lung injury induced by pyrrolizidine alkaloids
Author:
Funder
Research Grant Council of Hong Kong
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-023-03443-1.pdf
Reference40 articles.
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2. Burton VJ, Holmes AM, Ciuclan LI et al (2011) Attenuation of leukocyte recruitment via CXCR1/2 inhibition stops the progression of PAH in mice with genetic ablation of endothelial BMPR-II. Blood 118(17):4750–4758. https://doi.org/10.1182/blood-2011-05-347393
3. Castagnoli N, Rimoldi JM, Bloomquist J, Castagnoli KP (1997) Potential metabolic bioactivation pathways involving cyclic tertiary amines and azaarenes. Chem Res Toxicol 10(9):924–940. https://doi.org/10.1021/tx970096j
4. Dumitrascu R, Koebrich S, Dony E et al (2008) Characterization of a murine model of monocrotaline pyrrole-induced acute lung injury. BMC Pulm Med 8:25. https://doi.org/10.1186/1471-2466-8-25
5. Edgar JA, Molyneux RJ, Colegate SM (2015) Pyrrolizidine Alkaloids: potential role in the etiology of cancers, pulmonary hypertension, congenital anomalies, and liver disease. Chem Res Toxicol 28(1):4–20. https://doi.org/10.1021/tx500403t
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