Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening
Author:
Funder
ALIVE Foundation
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/article/10.1007/s00204-016-1756-1/fulltext.html
Reference78 articles.
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2. Anson BD, Kolaja KL, Kamp TJ (2011) Opportunities for use of human iPS cells in predictive toxicology. Clin Pharmacol Ther 89(5):754–758
3. Antherieu S, Chesne C, Li R, Guguen-Guillouzo C, Guillouzo A (2012) Optimization of the HepaRG cell model for drug metabolism and toxicity studies. Toxicol In Vitro 26(8):1278–1285. doi: 10.1016/j.tiv.2012.05.008
4. Asplund A, Pradip A, van Giezen M et al (2016) One standardized differentiation procedure robustly generates homogenous hepatocyte cultures displaying metabolic diversity from a large panel of human pluripotent stem cells. Stem Cell Rev 12(1):90–104. doi: 10.1007/s12015-015-9621-9
5. Baxter MA et al (2010) Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening. Stem Cell Res 5(1):4–22
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