A framework for the use of single-chemical transcriptomics data in predicting the hazards associated with complex mixtures of polycyclic aromatic hydrocarbons

Author:

Labib Sarah,Williams Andrew,Kuo Byron,Yauk Carole L.,White Paul A.,Halappanavar Sabina

Funder

Health Canada

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference45 articles.

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2. Benford D, DiNovi M, Setzer RW (2010) Application of the margin-of-exposure (MoE) approach to substances in food that are genotoxic and carcinogenic e.g.: benzo[a]pyrene and polycyclic aromatic hydrocarbons. Food Chem Toxicol. doi: 10.1016/j.fct.2009.09.039

3. Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc 57:289–300

4. Bhatnagar RS, Hussain MZ, Lee SD (1980) Benzo(a)pyrene alters lung collagen synthesis in organ culture. In: Pepelko WE, Danner RM, Clarke NA (eds) Health effects of diesel engine emissions. Proceedings of an international symposium, volume 1. United States Environmental Protection Agency, Cincinnati, OH, p 416

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