Constitutive androstane receptor (CAR) mediates dieldrin-induced liver tumorigenesis in mouse

Author:

Wang Zemin,Wu Qiangen,Li Xilin,Klaunig James E.ORCID

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference46 articles.

1. ATSDR (2002) Toxicological profile for Aldrin/Dieldrin. Atlanta, GA: Agency for Toxic Substances and Disease Registry, U.S. Department of Health and Human Services, Public Health Service

2. Bachowski S, Kolaja KL, Ketcham CA, Stevenson DE, Walborg EF, Klaunig JE (1997) Role of oxidative stress in the mechanism of dieldrin's hepatotoxicity. Ann Clin Lab Sci 27(3):196–209

3. Bachowski S, Xu Y, Stevenson DE, Walborg EF Jr, Klaunig JE (1998) Role of oxidative stress in the selective toxicity of dieldrin in the mouse liver. Toxicol Appl Pharmacol 150(2):301–309. https://doi.org/10.1006/taap.1998.8372

4. Baker TK, Bachowski S, Stevenson DE, Walborg EF Jr, Klaunig JE (1995) Modulation of gap junctional intercellular communication in rodent, monkey and human hepatocyte by nongenotoxic compounds. Prog Clin Biol Res 391:71–80

5. Budinsky RA, Schrenk D, Simon T et al (2014) Mode of action and dose–response framework analysis for receptor-mediated toxicity: the aryl hydrocarbon receptor as a case study. Crit Rev Toxicol 44(1):83–119. https://doi.org/10.3109/10408444.2013.835787

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