Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine-Reference-Cited by-同舟云学术

Use of an in vitro–in silico testing strategy to predict inter-species and inter-ethnic human differences in liver toxicity of the pyrrolizidine alkaloids lasiocarpine and riddelliine

Published:2019-01-19 Issue:3 Volume:93 Page:801-818
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Ning Jia,Chen Lu,Strikwold Marije,Louisse Jochem,Wesseling Sebastiaan,Rietjens Ivonne M. C. M.

Funder

China Scholarship Council

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/article/10.1007/s00204-019-02397-7/fulltext.html

Reference64 articles.

1. Abdullah R, Alhusainy W, Woutersen J, Rietjens IMCM, Punt A (2016) Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I. Food Chem Toxicol 92:104–116

2. Adams IR, Hamlin KE, Jelinek CF, Phillips RF (1942) Structure of riddelliine, the alkaloid in Senecio riddellii. J Am Chem Soc 64:2760–2763

3. Bane A, Seboxa T, Mesfin G, Ali A, Tsegaye Y, M WT, Haile SGS T (2012) An outbreak of veno-occlusive liver disease in northern Ethiopia, clinical findings. Ethiop Med J 50(Suppl 2):9–16

4. Barter ZE, Tucker GT, Rowland-Yeo K (2013) Differences in Cytochrome P450-Mediated Pharmacokinetics Between Chinese and Caucasian Populations Predicted by Mechanistic Physiologically Based Pharmacokinetic Modelling. Clin Pharmacokinet 52(12):1085–1100

5. Bfr (2013) Pyrrolizidine alkaloids in herbal teas and teas. BfR opinion

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