Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro

Author:

Worek Franz,Seeger Thomas,Goldsmith Moshe,Ashani Yacov,Leader Haim,Sussman Joel S.,Tawfik Dan,Thiermann Horst,Wille Timo

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference47 articles.

1. Aldridge WN, Reiner E (1972) Enzyme inhibitors as substrates—interactions of esterases with esters of organophosphorus and carbamic acids. North-Holland Publishing Company, Amsterdam

2. Allon N, Raveh L, Gilat E, Cohen E, Grunwald J, Ashani Y (1998) Prophylaxis against soman inhalation toxicity in guinea pigs by pretreatment alone with serum butyrylcholinesterase. Toxicol Sci 43:121–128

3. Amitai G, Gaidukov L, Adani R, Yishay S, Yacov G, Kushnir M, Teitlboim S, Lindenbaum M, Bel P, Khersonsky O, Tawfik DS, Meshulam H (2006) Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase. FEBS J 273:1909–1919

4. Ancill RJ (1956) The blood volume of the normal guinea pig. J Physiol Lond 132:469–475

5. Ashani Y, Wins P, Wilson IB (1972) The inhibition of cholinesterase by diethyl phosphorochloridate. Biochim Biophys Acta 284:427–434

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