Quinone–thioether metabolites of hydroquinone play a dual role in promoting a vicious cycle of ROS generation: in vitro and in silico insights
Author:
Funder
Young Scientists Fund
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00204-019-02443-4.pdf
Reference44 articles.
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3. Bonke E, Zwicker K, Drose S (2015) Manganese ions induce H2O2 generation at the ubiquinone binding site of mitochondrial complex II. Arch Biochem Biophys 580:75–83. https://doi.org/10.1016/j.abb.2015.06.011
4. Cheeseright TJ, Mackey MD, Scoffin RA (2011) High content pharmacophores from molecular fields: a biologically relevant method for comparing and understanding ligands. Curr Comput Aided Drug Des 7(3):190–205
5. Dhingra R, Kirshenbaum LA (2015) Succinate dehydrogenase/complex II activity obligatorily links mitochondrial reserve respiratory capacity to cell survival in cardiac myocytes. Cell Death Dis 6:e1956. https://doi.org/10.1038/cddis.2015.310
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