GC–MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3,4-methylenedioxymethamphetamine (MDMA)
Author:
Funder
Fundação para a Ciência e a Tecnologia
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/article/10.1007/s00204-018-2314-9/fulltext.html
Reference73 articles.
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3. Antolino-Lobo I, Meulenbelt J, van den Berg M, van Duursen MB (2011) A mechanistic insight into 3,4-methylenedioxymethamphetamine (“ecstasy”)-mediated hepatotoxicity. Vet Q 31(4):193–205. https://doi.org/10.1080/01652176.2011.642534
4. Araujo AM, Carvalho M, Carvalho F, Bastos ML, Guedes de Pinho P (2017) Metabolomic approaches in the discovery of potential urinary biomarkers of drug-induced liver injury (DILI). Crit Rev Toxicol 47(8):633–649. https://doi.org/10.1080/10408444.2017.1309638
5. Araujo AM, Moreira N, Lima AR et al (2018) Analysis of extracellular metabolome by HS-SPME/GC–MS: optimization and application in a pilot study to evaluate galactosamine-induced hepatotoxicity. Toxicol Lett 295:22–31. https://doi.org/10.1016/j.toxlet.2018.05.028
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