Mixture prioritization and testing: the importance of toxicokinetics

Author:

Braeuning AlbertORCID,Marx-Stoelting Philip

Funder

Bundesinstitut für Risikobewertung (BfR)

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference7 articles.

1. Alarcan J, Sprenger H, Waizenegger J et al (2021) Transcriptomics analysis of hepatotoxicity induced by the pesticides imazalil, thiacloprid and clothianidin alone or in binary mixtures in a 28-day study in female Wistar rats. Arch Toxicol 95(3):1039–1053 https://doi.org/10.1007/s00204-020-02969-y

2. Beronius A, Zilliacus J, Hanberg A, Luijten M, van der Voet H, van Klaveren J (2020) Methodology for health risk assessment of combined exposures to multiple chemicals. Food Chem Toxicol 143:111520. https://doi.org/10.1016/j.fct.2020.111520

3. EFSA Panel on Plant Protection Products and their Residues (2008) Opinion of the scientific panel on plant protection products and their residues to evaluate the suitability of existing methodologies and if appropriate, the identification of new approaches to assess cumulative and synergistic risks from pesticides to human health with a view to set MRLs for those pesticides in the frame of regulation (EC) 396/2005. EFSA J 704:1–84

4. EFSA Panel on Plant Protection Products and their Residues (2009) Scientific opinion on risk assessment for a selected group of pesticides from the triazole group to test possible methodologies to assess cumulative effects from exposure through food from these pesticides on human health. EFSA J 7(9):1167

5. EFSA Panel on Plant Protection Products and their Residues (2013) Scientific opinion on the identification of pesticides to be included in cumulative assessment groups on the basis of their toxicological profile. EFSA J 11(7):3293

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