Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes-Reference-Cited by-同舟云学术

Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes

Published:2012-12-29 Issue:2 Volume:87 Page:337-345
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Schug Markus,Stöber Regina,Heise Tanja,Mielke Hans,Gundert-Remy Ursula,Godoy Patricio,Reif Raymond,Blaszkewicz Meinolf,Ellinger-Ziegelbauer Heidrun,Ahr Hans-Jürgen,Selinski Silvia,Günther Georgia,Marchan Rosemarie,Blaszkewicz Meinolf,Sachinidis Agapios,Nüssler Andreas,Oberemm Axel,Hengstler Jan G.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00204-012-0999-8.pdf

Reference30 articles.

1. Bauer A, Schumann A, Gilbert M, Wilhelm C, Hengstler JG, Schiller J, Fuchs B (2009) Evaluation of carbon tetrachloride-induced stress on rat hepatocytes by 31P NMR and MALDI-TOF mass spectrometry: lysophosphatidylcholine generation from unsaturated phosphatidylcholines. Chem Phys Lipids 159(1):21–29

2. Beekmann JM, Boess F, Hildebrand H, Kalkuhl A, Suter L (2006) Gene Expression analysis of the hepatotoxicant methapyrilene in primary rat hepatocytes: an interlaboratory study. Environ Health Perspect 114(1):92–99

3. Boess F, Kamber M, Romer S, Gasser R, Muller D, Albertini S, Suter L (2003) Gene expression in two hepatic cell lines, cultured primary hepatocytes, and liver slices compared to the in vivo liver gene expression in rats: possible implications for toxicogenomics use of in vitro systems. Toxicol Sci 73(2):386–402

4. Brown RP, Delp MD, Lindstedt SL, Rhomberg LR, Beliles RP (1997) Physiological parameter values for physiologically based pharmacokinetic models. Toxicol Ind Health 13:407–484

5. Calandre EP, Alferez N, Hassanein K, Azarnoff DL (1981) Methapyrilene kinetics and dynamics. Clin Pharmacol Ther 29:527–532

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