Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?-Reference-Cited by-同舟云学术

Are the current commercially available oximes capable of reactivating acetylcholinesterase inhibited by the nerve agents of the A-series?

Published:2022-06-06 Issue:9 Volume:96 Page:2559-2572
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Santos Marcelo C.^ORCID,Botelho Fernanda D.^ORCID,Gonçalves Arlan S.^ORCID,Kitagawa Daniel A. S.^ORCID,Borges Caio V. N.^ORCID,Carvalho-Silva Taynara^ORCID,Bernardo Leandro B.,Ferreira Cíntia N.,Rodrigues Rafael B.,Ferreira Neto Denise C.^ORCID,Nepovimova Eugenie^ORCID,Kuča Kamil^ORCID,LaPlante Steven R.^ORCID,Lima Antonio L. S.^ORCID,França Tanos C. C.^ORCID,Cavalcante Samir F. A.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00204-022-03316-z.pdf

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2. Allgardsson A, Berg L, Akfur C et al (2016) Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6. Proc Natl Acad Sci 113(20):5514–5519

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4. Bajgar J, Fusek J, Kuca K, Bartosova L, Jun D (2007) Treatment of organophosphate intoxication using cholinesterase reactivators: facts and fiction. Mini Rev Med Chem 7(5):461–466

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