Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00204-008-0295-9.pdf
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4. Brüning T, Lammert M, Kempkes M, Thier R, Golka K, Bolt HM (1997) Influence of polymorphisms of GSTM1 and GSTT1 for risk of renal cell cancer in workers with long-term high occupational exposure to trichloroethene. Arch Toxicol 71:596–599
5. Chambers AF, Groom AC, Mac Donald IC (2002) Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2:563–572
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