Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity-Reference-Cited by-同舟云学术

Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicity

Published:2013-06-01 Issue:8 Volume:87 Page:1581-1593
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Schyschka L.,Sánchez J. J. Martínez,Wang Z.,Burkhardt B.,Müller-Vieira U.,Zeilinger K.,Bachmann A.,Nadalin S.,Damm G.,Nussler A. K.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00204-013-1080-y.pdf

Reference38 articles.

1. Agarwal R, MacMillan-Crow LA et al (2011) Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase. J Pharmacol Exp Ther 337(1):110–116

2. Aleksunes LM, Augustine LM et al (2007) Influence of acetaminophen vehicle on regulation of transporter gene expression during hepatotoxicity. J Toxicol Environ Health A 70(21):1870–1872

3. Arndt K, Haschek WM et al (1989) Mechanism of dimethylsufoxide protection against acetaminophen hepatotoxicity. Drug Metab Rev 20:261–269

4. Bruschi SA (2004) Methods and approaches to study metabolism and toxicity of acetaminophen. In: Drug metabolism and transport. Totowa, NJ, pp 197–232

5. Cole SP, Deeley RG (2006) Transport of gluthathione and gluthathione conjugates by MRP1. Trends Pharmacol Sci 27(8):438–446

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