Toxicokinetics, in vivo metabolic profiling, and in vitro metabolism of gelsenicine in rats-Reference-Cited by-同舟云学术

Toxicokinetics, in vivo metabolic profiling, and in vitro metabolism of gelsenicine in rats

Published:2022-01-23 Issue:2 Volume:96 Page:525-533
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Xiang Zheng^ORCID,Qiu Jieying,He Xiaoying,Yu Xinwei

Funder

National Natural Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

https://link.springer.com/content/pdf/10.1007/s00204-021-03209-7.pdf

Reference30 articles.

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2. Gao MY, Shen WZ, Wu YH, Cao CS, Zhang DM, Gao JH (2012) Study on anti-proliferation activity and the mechanisms of alkaloid monomers from Gelsemium elegans on HepG2 cell in vitro. J Chin Med Mater 35(3):438–442

3. Ji SJ, Liu W (2017) Simultaneous quantitative analysis of koumine, gelsemine and gelsenicine in biological samples by LC–MS/MS. Fa Yi Xue Za Zhi 33(2):141–147. https://doi.org/10.3969/j.issn.1004-5619.2017.02.007

4. Jin GL, Su YP, Liu M et al (2014) Medicinal plants of the genus Gelsemium (Gelsemiaceae, Gentianales)—a review of their phytochemistry, pharmacology, toxicology and traditional use. J Ethnopharmacol 152(1):33–52. https://doi.org/10.1016/j.jep.2014.01.003

5. Kitajima M, Nakamura T, Kogure N et al (2006) Isolation of gelsedine-type indole alkaloids from Gelsemium elegans and evaluation of the cytotoxic activity of gelsemium alkaloids for A431 epidermoid carcinoma cells. J Nat Prod 69(4):715–718. https://doi.org/10.1021/np060016o

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