A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies-Reference-Cited by-同舟云学术

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A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies

Published:2014-03-06 Issue: Volume: Page:
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Ramaiahgari Sreenivasa C.,den Braver Michiel W.,Herpers Bram,Terpstra Valeska,Commandeur Jan N. M.,van de Water Bob,Price Leo S.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00204-014-1215-9.pdf

Reference50 articles.

1. Abe K, Bridges AS, Brouwer KL (2009) Use of sandwich-cultured human hepatocytes to predict biliary clearance of angiotensin II receptor blockers and HMG-CoA reductase inhibitors. Drug Metab Dispos 37(3):447–452

2. Asthana A, Kisaalita WS (2012) Microtissue size and hypoxia in HTS with 3D cultures. Drug Discov Today 17(15–16):810–817

3. Bahrami A, Truong LD, Ro JY (2008) Undifferentiated tumor: true identity by immunohistochemistry. Arch Pathol Lab Med 132(3):326–348

4. Beggs KM, Fullerton AM, Miyakawa K, Ganey PE, Roth RA (2014) Molecular mechanisms of hepatocellular apoptosis induced by trovafloxacin-tumor necrosis factor-alpha interaction. Toxicol Sci 137(1):91–101

5. Chen G, Li S, Dong X et al (2012) Investigation of testosterone, androstenone, and estradiol metabolism in HepG2 cells and primary culture pig hepatocytes and their effects on 17betaHSD7 gene expression. PLoS ONE 7(12):e52255

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