Impact of the EndoPredict genomic assay on treatment decisions for oestrogen receptor-positive early breast cancer patients: benefits of physician selective testing

Author:

Dinh Phuong,Graham J. Dinny,Elder Elisabeth N.,Kabir Masrura,Doan Tram B.,French James,Meybodi Farid,Hui Rina,Wilcken Nicholas R.,Harnett Paul R.,Hsu Jeremy,Stuart Kirsty E.,Wang Tim,Ahern Verity,Brennan Meagan,Fox Stephen B.,Dear Rachel F.,Lim Elgene,White Michelle,Mann G. Bruce,Pathmanathan NirmalaORCID

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference22 articles.

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2. Piccart M, van’t Veer LJ, Poncet C, Lopes Cardozo JMN, Delaloge S, Pierga JY, Vuylsteke P, Brain E, Vrijaldenhoven S, Neijenhuis PA, Causeret S, Smilde TJ, Viale G, Glas AM, Delorenzi M, Sotiriou C, Rubio IT, Kummel S, Zoppoli G, Thompson AM, Matos E, Zaman K, Hilbers F, Fumagalli D, Ravdin P, Knox S, Tryfonidis K, Peric A, Meulemans B, Bogaerts J, Cardoso F, Rutgers EJT (2021) 70-gene signature as an aid for treatment decisions in early breast cancer: updated results of the phase 3 randomised MINDACT trial with an exploratory analysis by age. Lancet Oncol 22:476–488. https://doi.org/10.1016/S1470-2045(21)00007-3

3. Sparano JA, Gray RJ, Makower DF, Pritchard KI, Albain KS, Hayes DF, Geyer CE Jr, Dees EC, Goetz MP, Olson JA Jr, Lively T, Badve SS, Saphner TJ, Wagner LI, Whelan TJ, Ellis MJ, Paik S, Wood WC, Ravdin PM, Keane MM, Gomez Moreno HL, Reddy PS, Goggins TF, Mayer IA, Brufsky AM, Toppmeyer DL, Kaklamani VG, Berenberg JL, Abrams J, Sledge GW Jr (2018) Adjuvant chemotherapy guided by a 21-gene expression assay in breast cancer. N Engl J Med 379:111–121. https://doi.org/10.1056/NEJMoa1804710

4. Blank PR, Filipits M, Dubsky P, Gutzwiller F, Lux MP, Brase JC, Weber KE, Rudas M, Greil R, Loibl S, Szucs TD, Kronenwett R, Schwenkglenks M, Gnant M (2015) Cost-effectiveness analysis of prognostic gene expression signature-based stratification of early breast cancer patients. Pharmacoeconomics 33:179–190. https://doi.org/10.1007/s40273-014-0227-x

5. Dubsky P, Brase JC, Jakesz R, Rudas M, Singer CF, Greil R, Dietze O, Luisser I, Klug E, Sedivy R, Bachner M, Mayr D, Schmidt M, Gehrmann MC, Petry C, Weber KE, Fisch K, Kronenwett R, Gnant M, Filipits M, Austrian B, Colorectal Cancer Study G (2013) The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2- breast cancer patients. Br J Cancer 109:2959–2964. https://doi.org/10.1038/bjc.2013.671

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1. Molecular Profiling and Personalized Medicine in Drug-Resistant Breast Cancer;Overcoming Breast Cancer Therapy Resistance;2024

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