CIB1 depletion impairs cell survival and tumor growth in triple-negative breast cancer

Author:

Black Justin L.,Harrell J. Chuck,Leisner Tina M.,Fellmeth Melissa J.,George Samuel D.,Reinhold Dominik,Baker Nicole M.,Jones Corbin D.,Der Channing J.,Perou Charles M.,Parise Leslie V.

Funder

National Heart, Lung, and Blood Institute

North Carolina Translational and Clinical Sciences Institute

American Heart Association

National Cancer Institute

North Carolina Biotechnology Center

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference41 articles.

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3. Mirzoeva OK, Das D, Heiser LM, Bhattacharya S, Siwak D, Gendelman R, Bayani N, Wang NJ, Neve RM, Guan Y, Hu Z, Knight Z, Feiler HS, Gascard P, Parvin B, Spellman PT, Shokat KM, Wyrobek AJ, Bissell MJ, McCormick F, Kuo WL, Mills GB, Gray JW, Korn WM (2009) Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res 69(2):565–572. doi: 10.1158/0008-5472.CAN-08-3389

4. Hoeflich KP, O’Brien C, Boyd Z, Cavet G, Guerrero S, Jung K, Januario T, Savage H, Punnoose E, Truong T, Zhou W, Berry L, Murray L, Amler L, Belvin M, Friedman LS, Lackner MR (2009) In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models. Clin Cancer Res: Off J Am Assoc Cancer Res 15(14):4649–4664. doi: 10.1158/1078-0432.CCR-09-0317

5. Shimizu T, Tolcher AW, Papadopoulos KP, Beeram M, Rasco DW, Smith LS, Gunn S, Smetzer L, Mays TA, Kaiser B, Wick MJ, Alvarez C, Cavazos A, Mangold GL, Patnaik A (2012) The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer. Clin Cancer Res: Off J Am Assoc Cancer Res 18(8):2316–2325. doi: 10.1158/1078-0432.CCR-11-2381

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