The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s10549-005-9017-7.pdf
Reference22 articles.
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2. Takekawa M, Adachi M, Nakahata A, Nakayama I, Itoh F, Tsukuda H, Taya Y, Imai K, 2000 p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation EMBO J 19: 6517–6526
3. Lavoie JN, L’Allemain G, Brunet A, Muller R, Pouyssegur J, 1996 Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway J Biol Chem 271: 20608–20616
4. Bulavin DV, Higashimoto Y, Popoff IJ, Gaarde WA, Basrur V, Potapova O, Appella E, Fornace AJ Jr, 2001 Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase Nature 411: 102–107
5. Bulavin DV, Demidov ON, Saito S, Kauraniemi P, Phillips C, Amundson SA, Ambrosino C, Sauter G, Nebreda AR, Anderson CW, Kallioniemi A, Fornace AJ,Jr, Appella E, 2002 Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity Nat Genet 31: 210–215
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