Never use anthracyclines with trastuzumab: it is time to reconsider the taboo
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s10549-009-0402-5.pdf
Reference23 articles.
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3. Sawyer DB, Zuppinger C, Miller TA et al (2002) Modulation of anthracycline-induced myofibrillar disarray in rat ventricular myocytes by neuregulin-1b and anti-erbB2. Potential mechanism for trastuzumab-induced cardiotoxicity. Circulation 105:1551–1554
4. Peng X, Chen B, Lim CC, Sawyer DB (2005) The cardiotoxicology of anthracycline chemotherapeutics: translating molecular mechanism into preventative medicine. Mol Interv 5(3):163–171
5. Ewer MS, VooletichMT DurandJB et al (2005) Reversibility of trastuzumab-related cardiotoxicity: newinsights based on clinical course and response to medical treatment. J Clin Oncol 23:7820–7826
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1. Pegylated liposomal doxorubicin in combination with cyclophosphamide and trastuzumab in HER2-positive metastatic breast cancer patients: efficacy and cardiac safety from the GEICAM/2004–05 study;Annals of Oncology;2011-12
2. Baseline diastolic dysfunction as a predictive factor of trastuzumab-mediated cardiotoxicity after adjuvant anthracycline therapy in breast cancer;Breast Cancer Research and Treatment;2011-09-15
3. First-line chemotherapy with or without biologic agents for metastatic breast cancer;Critical Reviews in Oncology/Hematology;2010-11
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