The role of topoisomerase IIα in predicting sensitivity to anthracyclines in breast cancer patients: a meta-analysis of published literatures

Author:

Du Yueyao,Zhou Qiong,Yin Wenjin,Zhou Liheng,Di Genhong,Shen Zhenzhou,Shao Zhimin,Lu Jinsong

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference19 articles.

1. Berger JM, Gamblin SJ, Harrison SC, Wang JC (1996) Structure and mechanism of DNA topoisomerase II. Nature 379:225–232

2. Kellner U, Sehested M, Jensen PB, Gieseler F, Rudolph P (2002) Culprit and victim—DNA topoisomerase II. Lancet Oncol 3:235–243

3. Oakman C, Moretti E, Galardi F, Santarpia L, Di Leo A (2009) The role of topoisomerase IIalpha and HER-2 in predicting sensitivity to anthracyclines in breast cancer patients. Cancer Treat Rev 35:662–667

4. Durbecq V, Paesmans M, Cardoso F et al (2004) Topoisomerase-II alpha expression as a predictive marker in a population of advanced breast cancer patients randomly treated either with single-agent doxorubicin or single-agent docetaxel. Mol Cancer Ther 3:1207–1214

5. Di Leo A, Gancberg D, Larsimont D et al (2002) HER-2 amplification and topoisomerase IIalpha gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin Cancer Res 8:1107–1116

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