Regulation of cell survival by HUNK mediates breast cancer resistance to HER2 inhibitors
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s10549-014-3227-9.pdf
Reference33 articles.
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3. Quintela-Fandino M, Arpaia E, Brenner D, Goh T, Yeung FA, Blaser H, Alexandrova R, Lind EF, Tusche MW, Wakeham A et al (2010) HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1. Proc Natl Acad Sci USA 107(6):2622–2627
4. Yeh ES, Yang TW, Jung JJ, Gardner HP, Cardiff RD, Chodosh LA (2011) Hunk is required for HER2/neu-induced mammary tumorigenesis. J Clin Invest 121(3):866–879
5. Yeh ES, Belka GK, Vernon AE, Chen CC, Jung JJ, Chodosh LA (2013) Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten. Proc Natl Acad Sci USA 110(15):6103–6108
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