Multi-omics analyses provide novel biological insights to distinguish lobular ductal types of invasive breast cancers

Author:

Sivadas AmbilyORCID,Kok Victor C.ORCID,Ng Ka-LokORCID

Funder

Ministry of Science and Technology, Taiwan

Asia University Taiwan

The Wellcome Trust DBT India Alliance

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference62 articles.

1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F (2021) Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 71:209–249. https://doi.org/10.3322/caac.21660

2. Pestalozzi BC, Zahrieh D, Mallon E, Gusterson BA, Price KN, Gelber RD, Holmberg SB, Lindtner J, Snyder R, Thürlimann B, Murray E, Viale G, Castiglione-Gertsch M, Coates AS, Goldhirsch A (2008) Distinct clinical and prognostic features of infiltrating lobular carcinoma of the breast: combined results of 15 International Breast Cancer Study Group clinical trials. J Clin Oncol 26:3006–3014. https://doi.org/10.1200/jco.2007.14.9336

3. Weigelt B, Geyer FC, Natrajan R, Lopez-Garcia MA, Ahmad AS, Savage K, Kreike B, Reis-Filho JS (2010) The molecular underpinning of lobular histological growth pattern: a genome-wide transcriptomic analysis of invasive lobular carcinomas and grade- and molecular subtype-matched invasive ductal carcinomas of no special type. J Pathol 220:45–57. https://doi.org/10.1002/path.2629

4. Berx G, Cleton-Jansen AM, Strumane K, de Leeuw WJ, Nollet F, van Roy F, Cornelisse C (1996) E-cadherin is inactivated in a majority of invasive human lobular breast cancers by truncation mutations throughout its extracellular domain. Oncogene 13:1919–1925

5. Chen F, Ding K, Priedigkeit N, Elangovan A, Levine KM, Carleton N, Savariau L, Atkinson JM, Oesterreich S, Lee AV (2020) Single-cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells. Cancer Res 81:268–281. https://doi.org/10.1158/0008-5472.CAN-20-0696

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