A portrait of germline mutation in Brazilian at-risk for hereditary breast cancer

Author:

de Souza Timoteo Ana Rafaela,Gonçalves Ana Élida Menezes Magalhães,Sales Lucas Amadeus Porpino,Albuquerque Betina Menezes,de Souza Jorge Estefano Santana,de Moura Patrícia Cristina Pascoto,de Aquino Marcos Alberto Arruda,Agnez-Lima Lucymara Fassarela,Lajus Tirzah Braz PettaORCID

Funder

CNPq

PNPD/CAPES

FAPERN

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference52 articles.

1. Fitzmaurice C, Allen C, Barber RM et al (2017) Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015. JAMA Oncol 3:524. https://doi.org/10.1001/jamaoncol.2016.5688

2. INCA (2015) Estimativa 2016: incidência de Câncer no Brasil

3. Claus EB, Risch N, Thompson WD (1991) Genetic analysis of breast cancer in the cancer and steroid hormone study. Am. J. Hum. Genet. 48

4. Newman B, Austin MA, Lee M, King MC (1988) Inheritance of human breast cancer: evidence for autosomal dominant transmission in high-risk families. Proc Natl Acad Sci USA 85:3044–3048. https://doi.org/10.1073/pnas.85.9.3044

5. Abeliovich D, Kaduri L, Lerer I et al (1997) The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women. Am J Hum Genet 60:505–514

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