Hepatic uptake of gluconeogenic substrates in late-pregnant and mid-lactating rats-Reference-Cited by-同舟云学术

Hepatic uptake of gluconeogenic substrates in late-pregnant and mid-lactating rats

Published:1987-07-01 Issue:7 Volume:7 Page:587-592
ISSN:0144-8463
Container-title:Bioscience Reports
language:en
Short-container-title:

Author:

Casado Javier¹,Remesar Xavier¹,Pastor-Anglada Marçal¹

Affiliation:

1. Unitat de Bioquimica i Biologia Molecular B. Departament de Bioquímica i Fisiologia, Universitat de Barcelona, Facultat de Biologia, 08071 Barcelona, Spain

Abstract

Lactate uptake by liver is markedly increased in late-pregnant and mid-lactating rats without concomitant changes in its availability. Glycerol contribution to the liver 3-C unit uptake is only significant at term gestation (50% of lactate uptake) but almost negligible at mid-lactation (10% of lactate uptake). Pyruvate is only taken up by the liver of 15-day lactating rats. As a general trend, the livers of either pregnant or lactating rats are provided with an enhanced capacity to take up gluconeogenic substrates.

Publisher

Portland Press Ltd.

Subject

Cell Biology,Molecular Biology,Biochemistry,Biophysics

Link

https://portlandpress.com/bioscirep/article-pdf/7/7/587/472086/bsr0070587.pdf

Reference24 articles.

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2. Williamson, D. H. (1986). Regulation of metabolism during lactation in the rat.Reprod. Nutr. Develop. 26:597?603.

3. Leturque, A., Gilbert, M. and Girard, J. (1981). Glucose turnover during pregnancy in anaesthetized post-absorptive rats.Biochem. J. 196:633?636.

4. Burnol, A. F., Leturque, A., Ferré, P. and Girard, J. (1983). Glucose metabolism during lactation in the rat: quantitative and regulatory aspects.Am. J. Physiol. 245:E351-E358.

5. Smith, R. W. (1975). The effects of pregnancy and lactation on the activities in rat liver of some enzymes associated with glucose metabolism.Biochim. Biophys. Acta 411:222?229.

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