Interplay of Genotype and Substrate Stiffness in Driving the Hypertrophic Cardiomyopathy Phenotype in iPSC-Micro-Heart Muscle Arrays-Reference-Cited by-同舟云学术

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Interplay of Genotype and Substrate Stiffness in Driving the Hypertrophic Cardiomyopathy Phenotype in iPSC-Micro-Heart Muscle Arrays

Published:2021-06-25 Issue:5 Volume:14 Page:409-425
ISSN:1865-5025
Container-title:Cellular and Molecular Bioengineering
language:en
Short-container-title:Cel. Mol. Bioeng.

Author:

Guo Jingxuan,Jiang Huanzhu,Oguntuyo Kasoorelope,Rios Brandon,Boodram Zoë,Huebsch Nathaniel^ORCID

Funder

American Heart Association

National Institute of General Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,Modeling and Simulation

Link

https://link.springer.com/content/pdf/10.1007/s12195-021-00684-x.pdf

Reference67 articles.

1. Barefield, D., M. Kumar, J. Gorham, et al. Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice. J. Mol. Cell Cardiol. 79:234–243, 2015. https://doi.org/10.1016/j.yjmcc.2014.11.018.

2. Benjamin, E. J., S. S. Virani, C. W. Callaway, et al Heart Disease and Stroke Statistics - 2018 Update: A Report from the American Heart Association. 2018. https://doi.org/10.1161/CIR.0000000000000558.

3. Bers, D. M. Cardiac excitation–contraction coupling. Nature 415(January):198–205, 2002. https://doi.org/10.1201/b16783.

4. Birket, M. J., M. C. Ribeiro, G. Kosmidis, et al. Contractile defect caused by mutation in MYBPC3 revealed under conditions optimized for human article contractile defect caused by mutation in MYBPC3 revealed under conditions optimized for human PSC-cardiomyocyte function. Cell Rep. 13(4):733–745, 2015. https://doi.org/10.1016/j.celrep.2015.09.025.

5. Carrier, L., G. Mearini, K. Stathopoulou, and F. Cuello. Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology. Gene 573(2):188–197, 2015. https://doi.org/10.1016/j.gene.2015.09.008.

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2. Substrate mechanics unveil early structural and functional pathology in iPSC micro-tissue models of hypertrophic cardiomyopathy;iScience;2024-06

3. Three-dimensional cardiac models: a pre-clinical testing platform;Biochemical Society Transactions;2024-05-23

4. Gain of chromosome region 1q31.3 in human iPSCs confers growth advantage and alters contraction in derivative cardiomyocytes;2023-12-12

5. Dynamic control of contractile resistance to iPSC‐derived micro‐heart muscle arrays;Journal of Biomedical Materials Research Part A;2023-11-12

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