Differences in Proportion of N-acetyllactosamine and O-acetylated Sialic Acid Have No Significant Effect on the Pharmacokinetics and Biological Activity of Darbepoetin Alfa-Reference-Cited by-同舟云学术

Differences in Proportion of N-acetyllactosamine and O-acetylated Sialic Acid Have No Significant Effect on the Pharmacokinetics and Biological Activity of Darbepoetin Alfa

Published:2022-03-15 Issue:2 Volume:27 Page:244-252
ISSN:1226-8372
Container-title:Biotechnology and Bioprocess Engineering
language:en
Short-container-title:Biotechnol Bioproc E

Author:

Lee Won Jeong,Oh Hookeun,Choi Inseong,Lee Keunho,Shin Hyunwoo,Lee Yoon Jung,Park Jeehye,Yang Yoo Hee,Ha Gyong-Sik,Lee Dong-Eok,Choi Kang-Yell,Choi Eunyoung

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s12257-021-0042-0.pdf

Reference27 articles.

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3. Byrne, B., G. G. Donohoe, and R. O’Kennedy (2007) Sialic acids: carbohydrate moieties that influence the biological and physical properties of biopharmaceutical proteins and living cells. Drug Discov. Today. 12: 319–326.

4. Delorme, E., T. Lorenzini, J. Giffin, F. Martin, F. Jacobsen, T. Boone, and S. Elliott (1992) Role of glycosylation on the secretion and biological activity of erythropoietin. Biochemistry. 31: 9871–9876.

5. Egrie, J. C. and J. K. Browne (2001) Development and characterization of novel erythropoiesis stimulating protein (NESP). Nephrol. Dial. Transplant. 16 Suppl 3: 3–13.

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