Мікробіологічна характеристика та динаміка змін біоценозу тканин ясен у хворих на генералізований катаральний гінгівіт із хронічним та загостреним перебігом під впливом проведеної комплексної терапії

Abstract

Generalized catarrhal gingivitis occupies one of the first places among diseases of periodontal tissues in young people, which is confirmed by numerous studies of both foreign and domestic scientists.The aim of the study – to examine the condition of microbiocenosis of gingival tissues in patients with generalized catarrhal gingivitis with various clinical course, assessment of the effect of the proposed step-wise complex therapy on the clinical and laboratory indices of the disease.Materials and Methods. The article presents the data of a comparative analysis of gingival tissue microbiocoenos is peculiarities and the results of correction of the indices changes in 82 patients with generalized catarrhal gingivitis with variable clinical course.  The objective state of the oral cavity and gums was established on the basis of the dynamics of the following tests: a simplified hygiene index (OHI-S), Müllmann, Cowel, and papillary-marginal-alveolar index (PMA).Results and Discussion. To determine the biocenosis of gingival tissues, a classical bacterial culture method was used to determine the quantitative and specific composition of the microflora. Opportunistic streptococcal microflora of the oral cavity was found to occupy a leading role in the development of chronic catarrhal gingivitis, while staphylococci and the fungi of Candida genus are the main agents provoking exacerbations. A comprehensive treatment was elaborated and introduced into practice supposing the use of professional hygienic measures, anti-inflammatory, antibacterial, immunomodulating drugs and probiotics at different stages of treatment. Conclusions. The use of traditional antibiotic therapy in patients with chronic generalized catarrhal gingivitis with additional inclusion of bifidobacterin and cycloferon optimized the effectiveness of treatment: recovery of gum tissue was achieved in 93.5 % of patients and was accompanied by complete elimination of possible pathogens in the gingival tissues.