EARLY OUTCOMES OF TOTAL CORRECTION IN TETRALOGY OF FALLOT IN A TERTIARY CARE HOSPITAL OF PESHAWAR, KHYBER PAKHTUNKHWA, PAKISTAN; A TWO-YEAR RETROSPECTIVE STUDY

Abstract

Objective: To investigate the early outcomes of patients undergoing total-correction (TC) for Tetralogy of Fallot (TOF). Methodology: A retrospective study was carried out after acquiring Institutional ethical review committee approval. All patients diagnosed with TOF combined with pulmonary stenosis that had undergone primary repair between November 2016 and November 2018 at the Cardiothoracic Surgery Unit of Rehman Medical Institution, Peshawar were included while patients having anatomical defects alongside TOF were excluded from the study. Data was collected using a proforma. SPSS version 25 format was used for data entry and analysis. Comparisons between age related intraoperative parameters and age related early outcomes of the procedure was done by using the Student’s T-test and Chi-squared test keeping p ≤ 0.05 as significant. Results: A total of 186 patient’s data was retrieved from the hospital record. There were 109 (58.60%) males and 77 (41.40%) females. Mean cardiopulmonary bypass time (CBP) was 94.84±37.92 minutes and aortic cross clamp (ACC) time was 67.17±31.86 minutes. In the postoperative period, 11 (5.91%) patients developed Low cardiac output syndrome (LCOS).  Prolonged ventilator support (>24 hrs.) was required in 21(11.29%) patients and prolonged ICU stay (>48 hrs.) was seen in 38(20.43%) patients. A total of 166 (89.25%) patients were discharged while 20 (10.75%) died post operatively due to complications. Conclusion: Total repair for TOF is a favorable option in most patients as early outcomes were satisfactory with acceptable mortality rate after surgery.