Dried Cannabis Use, Tobacco Smoking, and COVID-19 Infection: Findings from a Longitudinal Observational Cohort Study

Author:

Milad Nadia,Belisario Kyla,MacKillop James,Hirota Jeremy

Abstract

Objective: The potential impact of cigarette and cannabis smoking on COVID-19 infection outcomes is not well understood. We investigated the association between combustible tobacco use and dried cannabis use with COVID-19 infection in a longitudinal cohort of community adults. Method: The sample comprised 1,343 participants, originally enrolled in 2018, who reported their cigarette and cannabis use in 11 assessments over 44 months, until 2022. COVID-19 infection history were self-reported after the onset of the pandemic. Univariate and multivariate logistic regression analyses were performed. The potentially confounding factor of vaccination status was also considered by stratifying data by booster vaccination self-reporting. Results: Among 1,343 participants, 820 (61.1%) reported any COVID-19 infection. Dried cannabis use (46.3% of participants, n = 721) was associated with higher self-reporting of 2+ COVID-19 infections (13.3% vs. 7.3% in non-users, p = .0004), while tobacco use (18.5% of participants, n = 248) had no significant effect (13.3% vs. 10.0% in no use group, p = .116). When stratified into single or dual substance use groups, dried cannabis-only use was associated with increased reporting of 1 or 2+ COVID-19 infections compared to substance non-users, while tobacco-only use and dual use groups were not significantly different from non-users. To account for differences in vaccination rates between substance use groups, we found that, among individuals with a COVID-19 booster vaccine, dried cannabis use was still associated with increased reporting of 2+ COVID-19 infections (p = .008). Conclusions: Our study suggests that dried cannabis use is associated with a higher likelihood of reporting 2+ COVID-19 infections. Although the study was observational and relied on self-report infection status, our findings support the need for further investigation into the impact of cannabis use on COVID-19 infection, particularly studies employing controlled experimental designs.

Publisher

Research Society on Marijuana

Reference56 articles.

1. Centers for Disease Controls. (2017, August 29). Adult Tobacco Use Glossary. https://www.cdc.gov/nchs/nhis/tobacco/tobacco_glossary.htm#print

2. Benjamin, D. J., Berger, J. O., Johannesson, M., Nosek, B. A., Wagenmakers, E. J., Berk, R., Bollen, K. A., Brembs, B., Brown, L., Camerer, C., Cesarini, D., Chambers, C. D., Clyde, M., Cook, T. D., De Boeck, P., Dienes, Z., Dreber, A., Easwaran, K., Efferson, C., Fehr, E., Fidler, F., Field, A. P., Forster, M., George, E. I., Gonzalez, R., Goodman, S., Green, E., Green, D. P., Greenwald, A. G., Hadfield, J. D., Hedges, L. V., Held, L., Hua Ho, T., Hoijtink, H., Hruschka, D. J., Imai, K., Imbens, G., Ioannidis, J. P. A., Jeon, M., Jones, J. H., Kirchler, M., Laibson, D., List, J., Little, R., Lupia, A., Machery, E., Maxwell, S. E., McCarthy, M., Moore, D. A., Morgan, S. L., Munafó, M., Nakagawa, S., Nyhan, B., Parker, T. H., Pericchi, L., Perugini, M., Rouder, J., Rousseau, J., Savalei, V., Schönbrodt, F. D., Sellke, T., Sinclair, B., Tingley, D., Van Zandt, T., Vazire, S., Watts, D. J., Winship, C., Wolpert, R. L., Xie, Y., Young, C., Zinman, J., & Johnson, V. E. (2018, Jan). Redefine statistical significance. Nature Human Behavior, 2(1), 6-10. https://doi.org/10.1038/s41562-017-0189-z

3. Blake, G. H., Abell, T. D., & Stanley, W. G. (1988). Cigarette smoking and upper respiratory infection among recruits in basic combat training. Annals of Internal Medicine, 109(3), 198-202. https://doi.org/10.7326/0003-4819-109-3-198

4. Bowdish, D. M. E., Chandran, V., Hitchon, C. A., Kaplan, G. G., Avina-Zubieta, J. A., Fortin, P. R., Larché, M. J., Boire, G., Gingras, A.-C., Dayam, R. M., Colmegna, I., Lukusa, L., Lee, J. L. F., Richards, D. P., Pereira, D., Watts, T. H., Silverberg, M. S., Bernstein, C. N., Lacaille, D., Benoit, J., Kim, J., Lalonde, N., Gunderson, J., Allard-Chamard, H., Roux, S., Quan, J., Hracs, L., Turnbull, E., Valerio, V., & Bernatsky, S. (2024). When should I get my next COVID-19 vaccine? Data from the surveillance of responses to COVID-19 vaccines in Systemic Immune-Mediated Inflammatory Diseases (SUCCEED) study. The Journal of Rheumatology, 51(7), 721-727. https://doi.org/10.3899/jrheum.2023-1214

5. Breznik, J. A., Rahim, A., Zhang, A., Ang, J., Stacey, H. D., Bhakta, H., Clare, R., Liu, L. M., Kennedy, A., Hagerman, M., Kajaks, T., Miller, M. S., Nazy, I., Bramson, J. L., Costa, A. P., & Bowdish, D. M. E. (2023). Early Omicron infection is associated with increased reinfection risk in older adults in long-term care and retirement facilities. EClinicalMedicine, 63, 102148. https://doi.org/10.1016/j.eclinm.2023.102148

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3