Follicular dendritic cell sarcoma of the spleen: A case report

Abstract

Follicular dendritic cell sarcomas (FDCS) are spindle cell lesions that are large, slow-growing masses in either nodal or  extranodal regions or both and originate from B-cell follicles of the lymph nodes. Most tumors originate from the cervical lymph nodes, but retroperitoneal and mediastinal origins have also been reported. Extranodal areas include soft tissues, skin, tonsils, gastrointestinal tract, liver, and spleen. The spleen is an uncommon location for an FDCS and for this reason, the tumor may be underdiagnosed or overlooked because of confusion with other solid tumors. In this study, we present a patient with a splenic FDCS who presented clinically with abdominal pain and diarrhea. The patient underwent a splenectomy and had an uneventful remission.