Affiliation:
1. Dept of Microbiology, Dr. S N Medical College, Jodhpur
2. Dept of Microbiology, Dr. S N Medical College, Jodhpur.
Abstract
Acute Febrile Encephalopathy is a clinical term used to describe patients presenting with short febrile illnesses with altered mental states.
Demographic distribution plays an essential role in the diagnosis of viral etiologies. One hundred ve suspected AFE cases were enrolled in the
study. A detailed history by predesigned performa and laboratory investigations was obtained for data collection. Viral etiology was diagnosed in
32 (30.48%) cases. The male to female ratio was 1.39:1. Total 56.25% of positive cases were from the lower class, 28.13% from the middle class,
and 15.63% from the upper class. 24 (75%) cases from rural, while only 8 (25%) of the urban population showed viral etiologies. In 19 (59.4%)
cases were either history of incomplete vaccination or not vaccinated, 13 (40.6%) cases had a history of complete immunization among positive
cases. The predominant clinical feature was fever (100%) followed by seizures 66(62.86%), vomiting 37(35.24%), headache 14(13.33%), paresis
in 16(15.24%) and altered sensorium in 29(27.62%), respectively. To conclude, the etiologic panorama of AFE varies with several factors such as
time and demographical location, age, and immunization status. There is an urgent need to conduct more studies to prole the viral etiologies
according to their prevalence in geographical areas so the treatment can be tailored accordingly and prophylaxis treatment or immunization can be
boosted in the population at risk of getting the disease.