RELATIONSHIP OF HYPOGONADISM & ERECTILE DYSFUNCTION IN PATIENTS OF TYPE II DIABETES PATIENTS IN NORTH BIHAR A CROSS SECTIONAL STUDY

Abstract

INTRODUCTION: Diabetes is a metabolic syndrome characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The persistent state of hyperglycemia has serious effects on virtually every body system, including but not limited to neuropathy, vasculopathy, as well as endocrinological changes, which all together lead to grave effects on the patient's quality of life. Androgen deciency has recently been identied as the dark side of type-II diabetes in male patients, leading to hypogonadism and erectile dysfunction. OBJECTIVES: Indentify any correlation between type II diabetes mellitus and the hypogonadism and erectile dysfunction. Search for any correlation between hypogonadism and glycemic parameters of the patients. MATERIALS AND METHODS: STUDYSETTING: DEPARTMENTOF MEDICINE, DARBHANGAMEDICALCOLLEGE & HOSPITAL, LAHERIASARAI, India. Total estimated sample size: 200 (group I-100 samples, group 2-100samples) RESULTAND ANALYSIS: In Case Group, 53(53.0%) patients were smoker. In Control Group, 30(30.0%) patients were smoker. Association of SMOKING vs group was statistically signicant (p=0.0009). In Case Group, 85(85.0%) patients had NON SPECIFIC SYMPTOMS. In Control Group, 12(12.0%) patients had NON SPECIFIC SYMPTOMS. Association of NON SPECIFIC SYMPTOMS vs group was statistically signicant (p<0.0001). SUMMARYAND CONCLUSION:It was showed that difference of mean LH (mIU/ml) with both group was not statistically signicant. In Case Group, the mean total testosterone (ng/dl) (mean± s.d.) of patients was 192.2021± 118.6405 and In Control Group, the mean total testosterone (ng/dl) (mean± s.d.) of patients was 149.7200± 26.4812. Total testosterone was high in cases compared to control and that was statistically signicant.