ADRENAL GLAND TUMOURS: A 2-YEAR TERTIARY CARE HOSPITAL BASED CASE SERIES

Author:

Deka Muktanjalee1,Suhana Asreen2,Roy Surajit3,Saikia Birinchi Kumar4

Affiliation:

1. Associate Professor, Department of Pathology, Gauhati Medical College and Hospital, Guwahati, Assam, India.

2. Post-graduate trainee, Department of Pathology, Gauhati Medical College and Hospital, Guwahati, Assam, India.

3. Demonstrator, Department of Pathology, Gauhati Medical College and Hospital, Guwahati, Assam, India.

4. Consultant Pathologist, SRL Diagnostics, Guwahati, Assam, India.

Abstract

Introduction: Adrenal gland tumors are rare. Asymptomatic adrenal tumours are found in 2-10% of the population worldwide, out of which, adrenocortical carcinomas(ACC) have an incidence of 0.5-2 cases/million population/year. ACC accounts for 0.05% -0.2% of all malignancies with a bimodal age distribution, in the first two decades and then in the fifth decade. They can be asymptomatic and diagnosed as Incidentalomas or present with signs and symptoms of hormone imbalance. Materials and methods: In this 2 year hospital-based retrospective case series from June,2018 to May,2020 , 5 cases of adrenal gland tumors diagnosed in the Department of Pathology , GMCH, were retrieved from the archives and reviewed. Each case was analyzed with respect to age , sex, site and tumor characteristics. Results: In this 2-year period, 5 cases of adrenal tumors were found. The age range of the patients was 8-54 years. Out of 5 cases,2 cases were male and 3 cases were female. Out of 5 cases of , 4 were on the left side and 1 was on the right side.2 out of the 5 cases were diagnosed as Adrenocortical carcinoma(low grade), 1 as Phaeochromocytoma and 2 as Adrenocortical Adenoma. Conclusion: Adrenal gland tumors are rare, so the pathologic classification and determination of prognosis are very challenging.

Publisher

World Wide Journals

Reference36 articles.

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2. 2. Libé R (2015) Adrenocortical carcinoma (ACC): diagnosis, prognosis, and treatment. Front. Cell Dev. Biol. 3:45. doi: 10.3389/fcell.2015.00045

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4. 4. Abul K. Abbas, Vinay Kumar, Jon C. Aster. The Endocrine System.In:Robbins and Cotran-Pathologic Basis of Disease, 9th edition, 2014.p-1132.

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