THE EFFECT OF LOW VERSUS HIGH DOSE OF ANTI-SNAKE VENOM ON OUTCOMES AND ADVERSE EFFECTS IN SNAKE BITE CASES AT M.G.M. MEDICAL COLLEGE AND HOSPITAL, JAMSHEDPUR, JHARKHAND: A CROSS-SECTIONAL OBSERVATIONAL STUDY-Reference-Cited by-同舟云学术

THE EFFECT OF LOW VERSUS HIGH DOSE OF ANTI-SNAKE VENOM ON OUTCOMES AND ADVERSE EFFECTS IN SNAKE BITE CASES AT M.G.M. MEDICAL COLLEGE AND HOSPITAL, JAMSHEDPUR, JHARKHAND: A CROSS-SECTIONAL OBSERVATIONAL STUDY

Published:2020-12-01 Issue: Volume: Page:55-58
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

Pandey Sanjay Kumar¹,Murmu Vikram²,Sarkar P.³,Jana Debarshi⁴

Affiliation:

1. MBBS, MD (Medicine), Assistant Professor, M.G.M. Medical College, Jamshedpur, Jharkhand.

2. MBBS, MD (Medicine), Assistant Professor. M.G.M. Medical College, Jamshedpur, Jharkhand.

3. MBBS, MD (Medicine), Department of Medicine, Professor and Head of Department, M.G.M. Medical College, Jamshedpur, Jharkhand.

4. Young Scientist (DST), Institute of Post-Graduate Medical Education and Research, A.J.C. Bose Road, Kolkata, West Bengal, India-700020.

Abstract

Background: Snakebite is a significant problem in rural India. It is an occupational hazard and causes considerable morbidity and mortality. It is a significant financial burden on victims and hospitals. Fortunately, these bites are eminently treatable and curable. A lack of universal consensus for the dose of Anti Snake Venom(A.S.V.) exists. Low vs. high dose is the most debated topic. Dose-related adverse effects are enduring issues in the snake bite management protocols. Objective: To observe the effects of the low and high dose of A.S.V. on results and side effects in snake bite cases in MGMM COLLEGE and hospital in Jharkhand, India. Materials and Methods: We did a cross-sectional in the medical emergency and intensive care unit of M.G.M. Medical College, Jamshedpur. We analyze the prescriptions of 58 snakebite patients admitted to the I.C.U/emergency. We analyzed data during the study period of 3 months. We used descriptive statistics and Microsoft Excel 2007. Fisher's Exact Test is used to analyze statistically Result: A.K.I. was found in 5 (21%) low dose group and 9 (26%) high dose group, patients with neuroparalysis required ventilator/Ambu bag support in 3 (13%) low dose group and 6 (18%) patients high dose group. The hospital stay duration was 3.98 for the low dose group and 5.22 days for the high dose group. The mortality rate was 4% in the low dose group versus 6% in the high dose group. The manifestation of adverse effects of A.S.V. was also found to be significantly low in a low dose A.S.V. group Conclusion: we compared treatment outcomes and found low doses of A.S.V. may be utilized to optimize the effective dose and minimize its adverse effects. A beneficial trend for the low-dose group is seen.

Publisher

World Wide Journals

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