A STUDY OF THE CLINICAL, RADIOLOGICAL, CYTOLOGICAL AND HISTOPATHOLOGICAL CORRELATION OF SOLITARY THYROID NODULE

Author:

Chakraborty Asit1,Kumar Hajra Suniti2,Sengupta Pratip3,Chowdhury Debayan4

Affiliation:

1. RMO-cum-Clinical Tutor, Department of General Surgery, Maharaja Jitendra Narayan Medical College & Hospital, Coochbehar, West Bengal

2. Associate Professor, Department of General Surgery, Ramakrishna Mission Seva Pratishthan, Vivekananda Institute of Medical Sciences, Kolkata.

3. Professor, Department of General Surgery, Ramakrishna Mission Seva Pratishthan, Vivekananda Institute of Medical Sciences, Kolkata.

4. Senior Resident, Department of General Surgery, College of Medicine and Sagar Dutta Hospital, Kamarhati, Kolkata

Abstract

Background:Solitary thyroid lesions are a common presentation in the surgical OPD. The signicance of solitary nodule is its malignant potential. Thyroid nodule is an elusive clinical problem. Surgeons and Physicians are often required to make a diagnostic or management decision in its treatment. Aim and Objectives: To study the correlation between Clinical, Radiological, Cytological and Histopathological nding in patients who presented with “solitary thyroid nodule”. Materials and Methods: Study design: A prospective observational study, Study area: Ramakrishna Mission Seva Pratishthan Hospital, Kolkata, Study period: July 2019 to June 2022(3 years), Sample size: 40 patients, Inclusion criteria: Patients presenting with solitary thyroid nodule, Exclusion criteria: Patients with multinodular goitre, patients with carcinoma thyroid with distant metastasis, paediatric patients and those unwilling. Methodology: Thorough history, clinical examination, investigation (FNAC/USG/Isotope Scan, TSH), appropriate surgical intervention and HPE of excised specimen was done. Results: In our study of 40 cases, 28(70.0%) were colloid goiter, 7(17.5%) were papillary carcinoma, 2(5%) were follicular adenoma, 1(2.5%) was follicular carcinoma, 1(2.5%) was adenomatoid hyperplasia and 1(2.5%) was Hashimoto thyroiditis. 28(70%) cases underwent hemithyroidectomy, 11(27.5%) underwent total thyroidectomy and 1(2.5%) underwent hemithyroidectomy followed by revision total thyroidectomy. 2 cases of papillary carcinoma with enlarged neck nodes underwent total thyroidectomy with neck node dissection. Conclusion: Solitary nodule is most common in woman and in third and fourth decade of life, more common in the right lobe. USG and FNAC are common modalities of investigations with high specicity and sensitivity. Isotope scan is only indicated to conrm the toxic nodule. Malignancy reported in my study was 20%. Early diagnosis and prompt treatment will cure the disease since carcinoma thyroid is more curable amongst all cancers.

Publisher

World Wide Journals

Subject

Paleontology,Stratigraphy,Global and Planetary Change,Paleontology,Stratigraphy,Global and Planetary Change,Atmospheric Science,Environmental Science (miscellaneous),Global and Planetary Change,Management, Monitoring, Policy and Law,Atmospheric Science,General Environmental Science,Environmental Chemistry,Management, Monitoring, Policy and Law,Atmospheric Science,Geography, Planning and Development,Global and Planetary Change,Atmospheric Science,Global and Planetary Change,Atmospheric Science,Global and Planetary Change,Pharmacology,Toxicology,Pharmacology (medical),Cardiology and Cardiovascular Medicine,Complementary and alternative medicine,General Medicine

Reference16 articles.

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3. Dean DS, Gharib H. Epidemiology of thyroid nodules. Best Pract Res Clin Endocrinol Metab. 2008 Dec;22(6):901-11.

4. Melak T, Mathewos B, Enawgaw B, Damtie D. Prevalence and types of thyroid malignancies among thyroid enlarged patients in Gondar, Northwest Ethiopia: a three years institution based retrospective study. BMC Cancer. 2014 Dec 2;14:899.

5. DeLellis RA, Williams ED. Tumours of the thyroid and parathyroid. In: DeLellis A, Lloyd RV, Heitz PU, Eng C, editors. WHO Classification of Tumors-Pathology and Genetics-Tumors of Endocrine organs. 1st ed. Lyon: IARC Press; 2004. p. 51-56.

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