COMPLICATIONS OF IRON OVERLOAD IN BETA THALASSEMIA- AN AUTOPSY CASE REPORT

Author:

Balasubramanian Meenakshi1,Sangoi Niyati2

Affiliation:

1. Professor (Additional), Department of Pathology, T.N.M.C and Nair Hospital, Mumbai 400008.

2. Third Year Junior Resident, Department of Pathology, T.N.M.C and Nair Hospital, Mumbai 400008.

Abstract

Beta thalassemias are a common group of hereditary disorders that have a high incidence in south Asian countries like India. The following article presents an autopsy case report of a patient with beta thalassemia major discussing the various clinicopathological features, gross and histopathological ndings. Common causes of death in patients with beta thalassemia major, various screening modalities for early detection of carriers, diagnosis and treatment have also been discussed, along with the review of literature.

Publisher

World Wide Journals

Reference10 articles.

1. Kumar V, K Abbas A & C Aster J (2020). Robbins And Cotran Pathologic Basis Of Disease;10th Ed: 644-850.

2. Kremastinos DT, Farmakis D, Aessopos A, Hahalis G, Hamodraka E, Tsiapras D, Keren A. Beta-thalassemia cardiomyopathy: history, present considerations, and future perspectives. Circ Heart Fail. 2010 May;3(3):451-8.

3. Karimi M, Emadmarvasti V, Hoseini J, Shoja L. Major causes of hospital admission in Beta thalassemia major patients in southern iran. Iran J Pediatr. 2011 Dec;21(4):509-13.

4. Cappellini MD, Cohen A, Eleftheriou A, et al. Guidelines for the Clinical Management of Thalassaemia [Internet]. 2nd Revised edition. Nicosia (CY): Thalassaemia International Federation; 2008. Chapter 9, Infections in Thalassaemia Major.

5. Mishra AK, Tiwari A. Iron overload in Beta thalassaemia major and intermedia patients. Maedica (Bucur). 2013;8(4):328-332.

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