EFFECT OF INTRAMUSCULAR DROTAVERINE HYDROCHLORIDE AND CAMYLOFIN DIHYDROCHLORIDE ON CERVICAL DILATATION IN FIRST STAGE OF LABOUR

Abstract

Introduction: Labour is one of the most important aspect of a woman's life. Its duration affects not only the mother but also the foetus. Cervical dilatation is one of the most important factors which determines the duration of labour. Hence, there is a need to nd a cervical dilator which optimizes the rate of cervical dilatation and also has no adverse effect on the mother and the foetus. The prolonged duration of labour affects the pregnant woman by exposing her to maternal exhaustion, increased chance of instrumental delivery, infection, and post partum haemorrhage. Aim: To compare and evaluate the rate of cervical dilatation from onset of true labour pain to full dilatation of cervix in women receiving intramuscular Drotaverine hydrochloride and Camylon dihydrochloride. Type of study: Prospective study Study period: 2 years (April 2019 to March 2021) Material And Methods: This study is conducted in department of Obstetrics and Gynaecology of Patna Medical College & Hospital, Patna, amongst women attending antenatal clinic and emergency obstetric unit. This study is conducted in 100 women who are randomly divided into 2 groups of 50 each. Group I comprised of 50 women who are administered Drotaverine hydrochloride and Group II comprised of rest 50 women who are administered Camylon dihydrochloride. Result: This study is carried out to compare the efcacy of Drotaverine hydrochloride and Camylon dihydrochloride on cervical dilatation. Mean cervical dilatation rate is signicantly more in Group II than in Group I. Time interval from administration of drug to delivery is signicantly more in Group I than in Group II. Signicantly more women delivered after rst dosage in Group II than in Group I. Conclusion: Both the drugs have been found to be effective in reducing the duration of labour and pain. Out of the two drugs involved in the present study, Camylon dihydrochloride is more effective than Drotaverine hydrochloride in reducing the duration of labour.