A PROSPECTIVE STUDY ON ANTIMICROBIAL PROPHYLAXIS USE IN ORTHOPEDIC SURGICAL INPATIENTS AT A TERTIARY CARE HOSPITAL
-
Published:2023-02-01
Issue:
Volume:
Page:67-72
-
ISSN:
-
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
-
language:en
-
Short-container-title:ijsr
Author:
Lakkireddy Prabhat1, M S Ratnamani2, Sanjana D.3, Maqsood Maryam4, Jameel Khazra4, Raghu Gaddam4, Supraja Salluri4
Affiliation:
1. Sr. Consultant Orthopaedic Surgeon, Apollo Hospitals, Hyderabad 2. Head and Sr. Microbiology Consultant, Apollo Hospitals, Hyderabad, India 3. PharmD Supervisor, Sri Venkateshwara College of Pharmacy, Hyderabad, India 4. PharmD Intern, Apollo Hospitals MOU Sri Venkateshwara College of Pharmacy, Hyderabad, India
Abstract
Introduction: Surgical Antimicrobial Prophylaxis plays a crucial role in prevention of Surgical Site Infections which are potentially preventable
and are multifactorial in nature. Materials and Methods: Aprospective, observational, single centre study was conducted on 165 patients to study
the administration of surgical antimicrobial prophylaxis and incidence of surgical site infections. Results: Most common surgeries were Knee
Replacement, Hip replacement, Open Reduction Internal Fixations, and Closed Reduction and Manipulations. The most utilized drug irrespective
of surgical procedure was found to be cefuroxime at 1.5 grams, both preoperatively and post operatively. Out of 165 patients, 9 patients showed
signs of SSI (incidence rate:5.45%), while others had healthy wound recovery. Conclusion: The prevention of SSIs, while accounting for
signicant risk factors, avoiding increased postoperative hospital stay and escalated expenses justies the adoption of the practice of antimicrobial
prophylaxis and employment of a parameter-based detection and treatment.
Publisher
World Wide Journals
Subject
History,Immunology,Immunology and Allergy,Pulmonary and Respiratory Medicine,Public Health, Environmental and Occupational Health,Health Policy,Law,Sociology and Political Science,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,General Engineering,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Literature and Literary Theory,History,Cultural Studies,Political Science and International Relations
Reference29 articles.
1. Mirzaei , M., Pourmokhtari , M., & Sepahvand, E. (2019). Evaluation of Prescription Pattern of Antibiotic Prophylaxis in Patients Undergoing Orthopedic Surgical Procedures and Their Clinical Outcomes in Jahrom. Journal of Clinical Physiotherapy Research, 4(4), e25. https://doi.org/10.22037/jcpr.v4i3.28983 2. Borthakur, B., Kumar, S., Talukdar, M., & Bidyananda, A. (2016). Surgical site infection in orthopaedics. International Journal of Orthopaedics Sciences, 2, 113-117. 3. DiPiro, J. T., Kanji, S., Devlin, J. W. (2008 print). Antimicrobial Prophylaxis in Surgery: Pharmacotherapy: A Pathophysiologic Approach: New York: McGraw-Hill Medical,. MLA (7th ed.) Pages 2060-2073. 4. Agwuh, D. K. N., Helm, R., Kumar, T. February 2016: Guideline for Antimicrobial Use in the Orthopaedic and Trauma Department- Doncaster and Bassetlaw Hospitals – NHS foundation Trust 5. Elroy, W., Elizabeth, W., Margaret, K., Enjema, P., Dickson, N., Jules C, A. (December 2015): The Pros, Cons and Future of Antibiotic Therapy - African Journal of Integrated Health Vol 5: N°2; P. 13-19
|
|