ANTIMICROBIAL SUSCEPTIBILITY PROFILE OF PATIENTS OF UTI IN A TERTIARY CARE HOSPITAL

Abstract

BACKGROUND: Urinary tract infection (UTI) is one of the commonest infection in humans, mainly following instrumentation. Common causative pathogens include E.coli, Pseudomonas, Klebsiella, Proteus etc. Thus, the aim of this study was to determine causative urinary bacteria and assess their in vitro susceptibility pattern to commonly used antimicrobial drugs. MATERIALAND METHODS: One sample from each subject was considered. Total of 100 positive urine cultures were taken. RESULT: E. coli (55%) was the predominant organism followed by K. pneumoniae (15%) and pseudomonas (11%). Resistance of microbes was high towards cefoperazone/ sulbactam, piperacillin/ tazobactam, meropenem. CONCLUSION: Findings from the study revealed that E.coli is the most predominant etiology of UTIs followed by Klebsiella. The results show that the antimicrobial resistance patterns of the causes of UTI are highly variable. The multi-drug resistance pattern in these bacteria was high. Hence, it becomes essential to treat UTI patients based on microbiological susceptibility results.