AN INSTITUTION-BASED DETECTION OF ABNORMAL CERVICAL CYTOLOGY IN PAPANICOLAOU SMEARS

Abstract

Introduction: Cancer of the cervix is the fourth most common cancer among women in the world. It accounts for 9%-13% of all cancers in females. Cervical cancer is the most common cause of death among women in developing countries. Aim: To study the role of Pap smear in detecting premalignant and malignant lesions of cervix; and to determine the prevalence of various lesions. Materials and Methods: A retrospective study was conducted in pathology department of Shaheed Nirmal Mahato Medical College, Dhanbad, Jharkhand from January 2017 to December 2020 on patients meeting the mentioned inclusion and exclusion criteria. Results: A total of 3591 Pap smears were studied with respect to age group, clinical signs and symptoms, and cytology ndings. Most of the patients were in age group of 31–40 (44.30%) years. The Pap smear ndings revealed 35.90% as mild dysplasia (Low grade squamous intraepithelial lesion- LSIL/CIN-I) , 14.81% as moderate to severe dysplasia (High grade squamous intraepithelial lesion-HSIL/CIN-II,CIN-III), 0.29% as invasive carcinoma(suspected) besides 51% showed Negative for Intraepithelial Lesion or Malignancy ( Inammatory lesion as 44.70% and 6.30% as normal cytology. Mean age of the patients with diagnosis of LSIL was 30.3 years and for HSIL, it was 39.5 years. Conclusion: Premalignant and malignant lesions of cervix are not uncommon in our set up and cervical cytology by Papanicolaou (Pap) smears is an effective means of screening for cervical premalignant and malignant conditions. Nonspecic inammation and Low grade squamous intraepithelial lesion were most common nding among different age groups.