COMPARISON BETWEEN EFFECT OF INTRAVENOUS LIGNOCAINE AND KETAMINE IN ALLEVIATING PROPOFOL INJECTION PAIN IN PATIENTS UNDERGOING SURGERIES UNDER GENERAL ANAESTHESIA
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Published:2022-12-01
Issue:
Volume:
Page:17-18
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ISSN:
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Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
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language:en
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Short-container-title:IJAR
Author:
Kumar Saravana1, Jawahar Sivagurunathan2, Kulasekhar Ashok3
Affiliation:
1. Postgraduate, Department of Anaesthesiology, Chettinad Hospital and Research Institute Kelambakkam, Tamilnadu. 2. Postgraduate, Department of Anaesthesiology, Chettinad hospital and Research Institute, Kelambakkam, Tamilnadu. 3. Professor and HOD, Department of Anaesthesiology, Chettinad hospital and Research Institute, Kelambakkam, Tamilnadu.
Abstract
Background: Propofol is the most commonly used intravenous inducing agent. Sharp, burning or aching pain on
injection is a major problem. The cardiovascular response to the pain can aggravate adverse events in patients with history
of coronary artery disease Small boluses of ketamine, magnesium, dexmedetomidine, ondansetron, dexamethasone, lignocaine hydrochloride,
ketorolac, metoclopramide and opioids have been tried. To compare analgesic effe Aim: cts of using intravenous ketamine and lignocaine in
alleviating pain following propofol injection. A prospective randomized double blinded st Methods And Material: udy was conducted in
Chettinad Hospital and Research Institute, Kelambakkam among 50 participants undergoing surgeries under general anesthesia. Tourniquet was
applied midarm ,Group L was given 21.3mg of 2% lignocaine and Group K was given 15mg of ketamine. Tourniquet was removed after
30seconds and then 1/3rd dose of total dose of 2mg/kg propofol was given. Degree of injection pain was evaluated using Mccririck Hunter scale.
Results: Pain score on propofol injection was similar in both groups. Among the patients, 54% reported no pain,in that 76% patients were in
Group L and 52% patients in Group K. McCRIRICK AND HUNTER PAIN SCALE rating between two groups are similar with the p value of
more than 0.05. The pre-treatment of 15mg ketamine is as effective as 21.3mg 2% l Conclusions: ignocaine in reducing the severity of propofol
injection pain.
Publisher
World Wide Journals
Subject
Mechanical Engineering,General Engineering,Religious studies,Communication,Strategy and Management,Communication,Business and International Management,Economics and Econometrics,Communication,Philosophy,Communication,Law,Communication,Communication,Education,Applied Psychology,Communication,Social Psychology,Biomedical Engineering,General Medicine
Reference15 articles.
1. Thukral S, Gupta P, et al. Dexmedetomidine versus ketamine infusion to alleviate propofol injection pain: A prospective randomized and double-blind study. Indian J Anaesth vol. 59, No. 8,2015,pp. 488-92. 2. Sim JY, Lee SH, et al. Pain on injection with microemulsion propofol. Br J Clin Pharmacol vol. 67, No 3, 2009, pp.316-25. 3. Desousa KA, et al. Pain on propofol injection: Causes and remedies. Indian J Pharmacol Vol. 48, No. 6, 2016,pp. 617-623. 4. Matta JA, Cornett PM, et al.. General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. Proc Natl Acad Sci U S A Vol. 105, No. 25, 2008, pp. 8784-89. 5. Scott RP, Saunders DA, et al. Propofol: clinical strategies for preventing the pain of injection. Anaesthesia Vol. 43, No. 6, 1988, pp. 492-4
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