SURVIVALAND PROGNOSTIC FACTORS FOR GLIOBLASTOMA MULTIFORME: A RETROSPECTIVE SINGLE INSTITUTIONAL STUDY

Author:

Gill Maneet1,Srivastava Chinmaya1,Agarwal Sudhanshu1,Gautam Lokesh1

Affiliation:

1. Department of Neurosurgery, Army Hospital (R & R) , Delhi Cantt 10

Abstract

OBJECTIVE The purpose of the present retrospective analysis was to present and discuss clinical features (Patient specific and tumour specific) and various prognostic factors that predict the survival of the patients with Glioblastoma multiforme (GBM) and to compare the results with pre-existing literature. MATERIALS &METHODS A single institutional data of 221 patients of GBM was reviewed from 2014 to 2018. Data regarding patients’ factor,tumour factor and survival analysis were collected and based on the above factor’s survival outcome was calculated. RESULTS A total of 221 patients were analysed. 197 patients underwent resection and 24 patients underwent biopsy (Open or stereotactic). Patients had a mean age of 56.5 years at the time of diagnosis. Median survival in patients < 50 years was 9.21 months and > 50 years was 4.56 months. The overall survival was 4.27% for the entire cohort at the end of two years. CONCLUSION In patients with GBM overall survival and prognosis remains dismal.Standard treatment includes resection followed bychemo-radiation which has improved the overall survivaloutcome. However, the prognosis continues to remains poor.

Publisher

World Wide Journals

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