ACUTE DISSEMINATED ENCEPHALOMYELITIS (ADEM) AS A COMPLICATION OF CHADOX1 NCOV-19 RECOMBINANT (COVISHIELD) VACCINATION

Author:

Kanti Dutta Paurush1,Mandal Arpan2,Goswami Preetam3,Mondol Manabendra1

Affiliation:

1. Junior Resident, Department of General medicine, Burdwan medical college & hospital, West Bengal, India.

2. Associate Professor, Department of General Medicine, Burdwan medical college & hospital, West Bengal, India.

3. Junior Resident, Department of Pulmonary Medicine, Burdwan medical college & hospital, West Bengal, India.

Abstract

Acute disseminated encephalomyelitis (ADEM) is a demyelinating disorder presenting with myriad of neurological manifestations. We describe a case of a 22-year-old male presenting with bilateral lower motor neuron (LMN) facial nerve palsy with quadriparesis in a case of post Covisheild vaccination. T2-weighted Magnetic resonance imaging of brain revealed non-enhancing multifocal altered hyperintensity lesions, suggestive of ADEM. He was treated with methyl prednisolone and intravenous immunoglobulin, following which patient's clinical symptoms resolved. To conclude with, ADEM should be included in the differential in a patient presenting with bilateral LMN facial nerve palsy and upper motor neuron quadriparesis following COVID 19 vaccination.

Publisher

World Wide Journals

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